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Original Article | Open Access | Am. J. Pure Appl. Sci., 5(6), 138-147 | doi: 10.34104/ajpab.023.01380147

Assessment of Serum Levels of Free Tri-iodothyronine, Free Thyroxine and Thyroid Stimulating Hormone in Patients with Acne Vulgaris

Umme Salma Mail Img Orcid Img ,
Dilruba Begum Mail Img ,
Md. Rezaul Islam Mail Img ,
Tabassum Mahjabeen Mail Img ,
Sheam Ahmed Apu Mail Img ,
Sharmin Ferdous Mail Img ,
Shweta Halder Mail Img ,
Kaniz Fatema Mail Img ,
Farzana Hossain Mail Img ,
Towhidul Iqram Mail Img

Abstract

The study aimed to assess serum levels of free tri-iodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH) in patients with acne vulgaris and healthy subjects, to compare all the above-mentioned parameters between the two groups and to correlate severity of acne vulgaris with serum levels of free tri-iodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH). A total number of 120 participants of both genders were selected with ages ranging from 15 to 45 years based on inclusion and exclusion criteria. Among them, 60 subjects with acne vulgaris were considered as Group A who were further sub-grouped into mild, moderate, and severe according to severity. Sixty age-matched healthy subjects were included in Group B for comparison. The levels of serum-free tri-iodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH) were estimated. The study revealed significantly lower levels of FT4 (p-0.02) and significantly higher levels of TSH (p <0.001) in group A when compared with group B. The difference in FT3 level between group A and group B was not statistically significant (p-0.343). FT3, FT4, and TSH were positively correlated with the severity of the acne but statistically not significant. 

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Academic Editor

Md. Ekhlas Uddin Dipu, Managing Editor, Universe Publishing Group (UniversePG), Dhaka, Bangladesh.

Received

October 10, 2023

Accepted

November 15, 2023

Published

November 25, 2023

Article DOI: 10.34104/ajpab.023.01380147

Corresponding author

Umme Salma
Lecturer, Department of Physiology, Uttara Adhunik Medical College, Dhaka, Bangladesh.

Cite this article

Salma U, Begum D, Islam MR, Mahjabeen T, Apu SA, Ferdous S, Halder S, Fatema K, Hossain F, and Iqram T. (2023). Assessment of serum levels of free tri-iodothyronine, free thyroxine, and thyroid stimulating hormone in patients with acne vulgaris. Am. J. Pure Appl. Sci., 5(6), 138-147. https://doi.org/10.34104/ajpab.023.01380147

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