The study aimed to assess serum levels of free tri-iodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH) in patients with acne vulgaris and healthy subjects, to compare all the above-mentioned parameters between the two groups and to correlate severity of acne vulgaris with serum levels of free tri-iodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH). A total number of 120 participants of both genders were selected with ages ranging from 15 to 45 years based on inclusion and exclusion criteria. Among them, 60 subjects with acne vulgaris were considered as Group A who were further sub-grouped into mild, moderate, and severe according to severity. Sixty age-matched healthy subjects were included in Group B for comparison. The levels of serum-free tri-iodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH) were estimated. The study revealed significantly lower levels of FT4 (p-0.02) and significantly higher levels of TSH (p <0.001) in group A when compared with group B. The difference in FT3 level between group A and group B was not statistically significant (p-0.343). FT3, FT4, and TSH were positively correlated with the severity of the acne but statistically not significant.
Academic Editor
Md.
Ekhlas Uddin Dipu, Managing Editor, Universe Publishing Group (UniversePG),
Dhaka, Bangladesh.
Salma U, Begum D, Islam MR, Mahjabeen T, Apu SA, Ferdous S, Halder S, Fatema K, Hossain F, and Iqram T. (2023). Assessment of serum levels of free tri-iodothyronine, free thyroxine, and thyroid stimulating hormone in patients with acne vulgaris. Am. J. Pure Appl. Sci., 5(6), 138-147. https://doi.org/10.34104/ajpab.023.01380147