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Original Article | Open Access | | doi: 10.34104/ejmhs.020012015

In-Vitro Comparative Quality Evaluation of Marketed Cefuroxime 250 mg Tablets in Bangladesh

Md. Shahin Sarker ,
Md. Rafiqul Islam ,
Md. Selim Reza ,
Mir Imam Ibne Wahed

Abstract

ABSTRACT

The study evaluated different quality control parameters of five brands of Cefuroxime 250mg tablets which are already marketed in Bangladesh. Five brands of the drug sourced from different retail outlets to assess the quality assessment and comparison of the tablets using the in-vitro release study. The brands were subjected to various official tests including uniformity of weight, thickness test, dissolution tests, and cumulative % of drug release and friability test.  This research further focuses on the requirement of manufacturers to construct quality into their products during manufacture and also sustain the built-in quality from batch to batch in line with the principles of cGMP.


Keywords: In-Vitro, Cefuroxime 250mg, Quality evaluation, Comparative, and Physical parameter.


Citation: Sarker MS, Islam MR, Reza MS, and Wahed MII. (2020). In-vitro comparative quality evaluation of marketed cefuroxime 250 mg tablets in Bangladesh. Eur. J. Med. Health Sci., 2(1), 12-15. 

https://doi.org/10.34104/ejmhs.020012015


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Received

Accepted

Published

February 29, 2020

Article DOI: 10.34104/ejmhs.020012015

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